B7-33 6mg | 20-Vial Kit | RXFP1 Relaxin Analogue

B7-33 6mg | 20-Vial Kit | Single-chain RXFP1 agonist — relaxin B-chain analogue for anti-fibrotic, collagen remodelling, and cardiac fibrosis research. ≥99% HPLC purity, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$610

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SKU: QSC-B76-B733-6MG-20VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse

What is B7-33?

B7-33 is a single-chain peptide analogue of the relaxin-2 B-chain, engineered to selectively activate RXFP1 (relaxin family peptide receptor 1) while avoiding the native two-chain structure of relaxin-2. Studied for anti-fibrotic effects, collagen remodelling, vasodilation, and cardioprotection — without the insulin-like A-chain that complicates full relaxin manufacture. Represents a simplified, single-chain RXFP1 agonist for fibrosis and cardiovascular research. Research use only.

Research Applications

Anti-Fibrotic Research

Collagen I/III expression suppression, MMP upregulation, TGF-β pathway modulation

RXFP1 Receptor Pharmacology

Receptor binding kinetics, cAMP/PKA signalling, β-arrestin recruitment

Cardiac Fibrosis Models

Post-infarct remodelling, myocardial stiffness, cardiac fibroblast activity

Vasodilation & Vascular Biology

NO-mediated vasodilation, endothelial function, arterial compliance

Single-Chain Relaxin Analogue Studies

B7-33 vs full relaxin-2 pharmacodynamic comparison, potency, selectivity

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2413928-17-1
Molecular Formula Single-chain relaxin B-chain analogue, ~3,800 Da
Identity MS molecular weight confirmed — every batch
Peptide Type Relaxin B-Chain Peptide / RXFP1 Agonist
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (4 weeks)
Shelf Life 24 months (unopened)

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute B7-33?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear — dissolves within 1–2 minutes. The 6mg vial provides a concentrated stock suitable for dilution to working concentrations.
How should B7-33 be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 4 weeks. Avoid repeated freeze-thaw cycles. B7-33 is relatively stable due to its engineered single-chain structure.
Why use B7-33 instead of native relaxin-2?
Native human relaxin-2 is a two-chain peptide (A and B chains linked by disulfide bonds) requiring complex manufacture. B7-33 achieves selective RXFP1 agonism from a single synthesisable chain, enabling more reproducible research with comparable pharmacological activity at the receptor level.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 Shipping: China warehouse — 7–14 day global delivery

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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