QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is P21-Ada?
P21-Adamantane is a cntf-derived nootropic peptide analogue. Adamantane-conjugated analogue of P21, a CNTF fragment. Crosses the blood-brain barrier more readily than native P21; activates JAK-STAT3 and MAPK/ERK pathways, promoting BDNF upregulation, neuroplasticity, and cognitive enhancement in preclinical models. Research use only.
Research Applications
Neuroplasticity Research
BDNF upregulation, synaptic density, long-term potentiation studies
JAK-STAT3 / MAPK-ERK Signalling
Pathway activation, downstream transcription factor profiling
Cognitive Enhancement Models
Spatial memory, learning acquisition, recognition tasks in rodent models
Neuroprotection Studies
Oxidative stress resistance, neuronal survival, neuroinflammation
BBB Penetration Research
Adamantane lipophilicity, CNS bioavailability, transport mechanism studies
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | N/A (novel analogue) |
| Molecular Formula | N/A, MW N/A |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | CNTF-Derived Nootropic Peptide Analogue |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months (unopened) |

