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Matrixyl (Palmitoyl Pentapeptide-4) 10mg | Matrikine / Collagen-Stimulating

Matrixyl (Palmitoyl Pentapeptide-4) 10mg — Palmitoyl pentapeptide-4 (Pal-KTTKS) — TGF-β signalling activator studied for collagen I/III and fibronectin synthesis upregulation in fibroblast models for wound repair and anti-aging skin research. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
✓ Free Shipping on All Orders ✓ Ships from China (🇨🇳)

$190

or
SKU: QSC-MATRIXYL-10MG-10VIAL
Categories: China, Cosmetics Peptides, Research Peptides
Brand: QSC
Technical Specs & COA
PubMed
Disclaimer & Storage Guide

QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse

What is Matrixyl?

Matrixyl (Palmitoyl Pentapeptide-4) is a matrikine / collagen-stimulating peptide. Palmitoyl-Lys-Thr-Thr-Lys-Ser pentapeptide; mimics collagen breakdown fragments (matrikines) to upregulate collagen I, III, fibronectin, and hyaluronic acid synthesis via TGF-β pathway activation. Research use only.

Research Applications

Collagen Synthesis Research

Type I & III collagen upregulation, fibroblast activation, ECM remodelling

TGF-β Pathway Studies

TGF-β1 receptor activation, downstream SMAD signalling, gene expression

Skin Ageing Models

Wrinkle reduction, dermal thickness, elasticity studies in vitro/ex vivo

Wound Healing Research

Fibroblast proliferation, ECM scaffold restoration, tissue regeneration

Biomaterial & Cosmeceutical R&D

Penetration enhancer lipid conjugation, topical delivery optimisation

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 214047-00-4
Molecular Formula C₃₉H₇₅N₅O₁₀, MW 802.0
Identity MS molecular weight confirmed — every batch
Peptide Type Matrikine / Collagen-Stimulating Peptide
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months (unopened)

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 Shipping: China warehouse — 7–14 day global delivery
🧬 PubMed Research — (Palmitoyl
Search PubMed ↗
5,988 publications found Last 10 years 3 most recent shown
41709507
Phytochemical study of Homalanthus giganteus: isolation, antiproliferative activity, and computational mechanistic insights of tigliane diterpenes against colorectal cancer.
Wirasisya DG et al. · Pharm Biol 2026 View ↗
41830765
Extracellular vesicles-mediated delivery of SpCas9 RNPs for therapeutic gene editing in Spinocerebellar Ataxia Type 3.
Leandro K et al. · Biomaterials 2026 View ↗
41871748
From palmitoylation to cholesterol metabolism: The hidden mechanism of lung tumorigenesis.
Shen L et al. · Cell Signal 2026 View ↗

Showing 3 of 5,988 for (Palmitoyl

View all on PubMed ↗

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

📋

Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
🧪

General Safety & Handling

🚫

Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

🥽

PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

🌡️

Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

🗑️

Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

🧾

Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

❄️

Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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