Retatrutide 100mg | 10-Vial Kit | Triple GIP/GLP-1/Glucagon Agonist | Obesity & Metabolic Research

Retatrutide (LY3437943 / triple incretin agonist, CAS 2381932-72-3) 100mg — ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

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$750

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SKU: QSC-RETATRUTIDE-100MG-10VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping

What is Retatrutide??

Retatrutide (LY3437943, CAS 2381932-72-3) is a 39-amino acid triple-receptor agonist simultaneously activating the GIP receptor (GIPR), GLP-1 receptor (GLP-1R), and glucagon receptor (GCGR) — the first clinically investigated triagonist incretin peptide. Developed by Eli Lilly, it incorporates a C18 fatty diacid moiety for albumin binding, yielding a half-life of approximately 6 days. Phase 2 data demonstrated up to ~24% body weight reduction — exceeding tirzepatide (dual GIP/GLP-1) — primarily attributed to the additive glucagon receptor arm driving hepatic fat oxidation, thermogenesis, and appetite suppression independent of insulin secretion. Retatrutide is the leading research tool for dissecting the individual and combined contributions of all three incretin-related receptor axes.

Research Applications

Triple Receptor Dissection

GIPR vs. GLP-1R vs. GCGR individual arm contributions — selective antagonist co-treatment designs

Obesity & Thermogenesis

GCGR-mediated energy expenditure, brown adipose UCP1, hepatic fat oxidation — beyond dual incretin

Glucose Homeostasis

Triple incretin insulin secretion, glucagon regulation balance, hepatic glucose output at GCGR

NAFLD/NASH Research

Hepatic steatosis, liver fat quantification, fibrosis biomarkers under triple agonism

vs Tirzepatide Comparison

Dual (tirzepatide) vs. triple (retatrutide) incretin: weight loss depth, metabolic breadth, receptor kinetics

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2381932-72-3
Also Known As LY3437943, triple incretin agonist
Molecular Weight ~4681 Da
Half-Life ~6 days (C18 fatty diacid albumin binding)
Receptors GIPR + GLP-1R + GCGR (triple agonist)
Peptide Type Synthetic triple incretin receptor agonist — triagonist
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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