VIP 5mg | 10-Vial Kit | Vasoactive Intestinal Peptide | Neuropeptide & Anti-Inflammatory Research

VIP 5mg | 10-Vial Kit — Vasoactive intestinal peptide — VPAC1/VPAC2 receptor-mediated neuropeptide studied for bronchodilation, immunomodulation, circadian rhythm regulation via SCN, and anti-inflammatory effects in GI and pulmonary research. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$230

or
SKU: QSC-VIP-5MG-10VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS8-Region Domestic Shipping

What is VIP??

VIP (Vasoactive Intestinal Peptide, CAS 37221-79-7) is a 28-amino acid neuropeptide hormone (His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂) first isolated from porcine intestine. Molecular formula C₁₄₇H₂₃₇N₄₃O₄₃S, MW 3326.78 g/mol. VIP acts at VPAC1 and VPAC2 receptors (Gs/cAMP) broadly expressed in CNS, lung, gut, immune cells, and vasculature. It is a potent smooth muscle relaxant, bronchodilator, immunomodulator, and circadian pacemaker peptide (via VPAC2 in the SCN) — making it one of the most pleiotropic neuropeptides in research.

Research Applications

VPAC1/VPAC2 Receptor Pharmacology

Gs/cAMP signalling, receptor selectivity profiling, VPAC1 vs. VPAC2 tissue distribution

Immunomodulation

Anti-inflammatory: IL-10/TGF-β induction, IL-6/TNF-α suppression, Treg promotion, macrophage M2 polarisation

Pulmonary Research

Bronchodilation, pulmonary hypertension, airway smooth muscle relaxation, inflammatory lung models

Circadian Biology

SCN VPAC2-mediated circadian pacemaking, VIP neuron interneuron synchronisation, phase-shift studies

GI & Vascular Research

Intestinal smooth muscle relaxation, splanchnic vasodilation, gut hormone secretion, colitis models

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 37221-79-7
Sequence His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
Molecular Formula C₁₄₇H₂₃₇N₄₃O₄₃S
Molecular Weight 3326.78 g/mol
Receptors VPAC1 (VIPR1) + VPAC2 (VIPR2) — Gs/cAMP coupled
Peptide Type Endogenous 28-aa neuropeptide hormone / VPAC1/VPAC2 agonist
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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