ERRα is a key co-activator of PGC-1α target genes. SLU-PP-332 upregulates mitochondrial biogenesis markers (TFAM, NRF1, COX IV). Relevant for age-related mitochondrial decline research, sarcopenia, and muscle quality research.
Metabolic / Fat Oxidation Research
ERRα/γ activation in skeletal muscle and adipose increases fatty acid oxidation gene expression — complementary to PPARδ pathway. Studied for fat mass reduction, energy expenditure, and VO2max improvement in metabolic disease models.
Comparison vs PPARδ Agonists
SLU-PP-332 vs Cardarine (GW501516): distinct receptor mechanism, potentially additive gene programme activation. Research into whether ERR + PPARδ dual activation produces greater endurance and metabolic effects than either alone.
Key Research Data
Study
Key Findings
Dufour et al. 2007 Cell Metab
ERRα role in oxidative metabolism: knockout vs WT — ERRα essential for exercise-induced mitochondrial adaptation
ERRα is a key co-activator of PGC-1α target genes. SLU-PP-332 upregulates mitochondrial biogenesis markers (TFAM, NRF1, COX IV). Relevant for age-related mitochondrial decline research, sarcopenia, and muscle quality research….
Does QSC ship SLU-PP-332 to the USA?
Yes. QSC ships domestically across the USA and to EU, UK, Canada, and Australia. Every batch carries a Janoshik third-party COA confirming ≥99% HPLC purity and MS identity.
