QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Semaglutide?
Semaglutide (GLP-1 receptor agonist (94% homology to native GLP-1)) is a 31-amino acid fatty acid-conjugated peptide. Selective GLP-1 receptor agonist with 94% amino acid homology to native GLP-1, fatty acid conjugation enabling weekly dosing. Activates GLP-1R on pancreatic beta cells, hypothalamus, heart, and kidney — glucose-dependent insulin secretion, appetite suppression, gastric emptying delay, and direct cardiovascular effects. SELECT CVOT (2023): 20% MACE reduction.
Research Applications
GLP-1R Pharmacology
Receptor signalling, cAMP cascade, beta cell insulinotropic response
Metabolic Research
Type 2 diabetes, insulin secretion, OGTT models
Obesity & Appetite
Hypothalamic appetite suppression, gastric emptying delay
Cardiovascular
SELECT CVOT reference compound — 20% MACE reduction
NASH/Liver
Hepatic steatosis, NASH resolution, liver fibrosis models
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 910463-68-2 |
| Molecular Formula | C₁₈₇H₂₉₁N₄₅O₅₉ |
| Peptide Type | GLP-1 Receptor Agonist |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |




