What is Vardenafil?
Vardenafil is a selective phosphodiesterase type 5 (PDE5) inhibitor used clinically to treat erectile dysfunction. By inhibiting PDE5, it prevents the breakdown of cyclic GMP (cGMP) in smooth muscle cells of the corpus cavernosum, promoting vasodilation and increased blood flow.
It has a rapid onset of action and is often compared with other PDE5 inhibitors like sildenafil and tadalafil for its potency and pharmacokinetic profile.
Research Applications
- PDE5 enzyme inhibition studies
- Erectile dysfunction and sexual function research
- Smooth muscle relaxation and vasodilation studies
- Cardiovascular hemodynamics and blood pressure research
- Nitric oxide-cGMP signaling pathway investigations
- Comparative pharmacokinetic and pharmacodynamic studies of PDE5 inhibitors
- Pulmonary vascular function studies
Quick Product Specs
- Form: Oral Tablets
- CAS Number: 224785-91-5
- Chemical Name: (2S)-N-[(2S,3S)-3-(1-Methylpiperidin-4-yl)-2-(2-propoxyphenyl)sulfonylamino-3-phenylpropionyl]-2-pyrrolidinecarboxamide
- Storage: Room temperature (cool, dry place)
- Shelf Life: As indicated by manufacturer
- Type: Phosphodiesterase Type 5 (PDE5) Inhibitor
Certificate of Analysis (COA)

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