What is Testosterone Cypionate?
Testosterone Cypionate injectable (branded as Depo-Testosterone or generics) is a pharmaceutical oil-based solution for intramuscular administration, used primarily for testosterone replacement therapy (TRT) in adult males with hypogonadism (low or absent endogenous testosterone due to medical conditions like primary/secondary testicular failure).
The cypionate ester provides slow release from the injection site, with a biological half-life of approximately 8 days, enabling dosing every 1–4 weeks (commonly weekly or bi-weekly for stable blood levels in TRT). After injection, esterases hydrolyze the ester, releasing free testosterone that binds androgen receptors to support male sexual characteristics, muscle/bone maintenance, red blood cell production, and libido.
Research Applications
- Testosterone replacement in hypogonadism (primary/secondary)
- Pharmacokinetics/comparative ester studies (cypionate vs. enanthate/undecanoate)
- Effects on muscle, bone density, erythropoiesis, mood/libido
- Endocrine suppression/recovery dynamics
- Masculinizing hormone therapy in transgender care
- Treatment of delayed puberty or wasting conditions
Quick Product Specs
- Form: Injectable Solution (sterile, oil-based; clear, colorless to pale yellow viscous liquid)
- CAS Number: 58-20-8
- Chemical Name: Testosterone 17β-cyclopentylpropionate (or Androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17β)-)
- Storage: Controlled room temperature 20–25°C (68–77°F); excursions permitted 15–30°C (59–86°F); protect from light; do not refrigerate (may cause crystallization/cloudiness—warm gently to redissolve if occurs)
- Shelf Life: Typically 24–36 months unopened from manufacture date (pharmaceutical or lab vials); multi-dose vials discard 28 days after first puncture for sterility (per USP/manufacturer guidelines)
- Type: Long-acting injectable androgen/anabolic steroid (AAS); esterified testosterone; deep intramuscular injection only (gluteal preferred)
Certificate of Analysis (COA)

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