PTD-DBM 5mg | 20-Vial | Wnt/CXXC5 Pathway Modulator

PTD-DBM 5mg | 10-Vial Kit | Wnt pathway activator via CXXC5-Dishevelled interaction disruption — hair follicle regeneration and skin wound healing research. ≥99% HPLC, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$590

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SKU: QSC-PTD5-PTD-DBM-5MG-20VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse

What is PTD-DBM?

PTD-DBM is a cell-penetrating peptide construct combining a Protein Transduction Domain (PTD) and a Dvl-binding motif (DBM). It blocks the inhibitory CXXC5–Dishevelled interaction, restoring Wnt/β-catenin signalling. Studied for dermal papilla cell activation, hair follicle neogenesis, and wound healing. Research use only.

Research Applications

Wnt/β-Catenin Pathway Research

β-catenin nuclear translocation, TCF/LEF reporter assays, pathway activation

Hair Follicle Regeneration

Dermal papilla cell proliferation, anagen induction, follicle neogenesis models

Skin Wound Healing

Keratinocyte re-epithelialisation, fibroblast migration, ECM deposition

CXXC5 Biology

Wnt suppressor interaction, negative feedback loop, Dkk1 regulation

Cell-Penetrating Peptide Research

PTD transduction efficiency, intracellular delivery, nuclear targeting

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 2411025-13-3
Molecular Formula Proprietary peptide construct (PTD + DBM fusion)
Identity MS molecular weight confirmed — every batch
Peptide Type Wnt/CXXC5 Pathway Modulator
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (3 weeks)
Shelf Life 24 months (unopened)

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute PTD-DBM?
Add 1 mL bacteriostatic water to the lyophilized vial, directing liquid down the inner wall. Swirl gently until clear. PTD-DBM dissolves readily within 1–2 minutes due to its hydrophilic PTD domain.
How should PTD-DBM be stored?
Store lyophilized vials at −20°C. Reconstituted solution is stable at 2–8°C for up to 3 weeks. Minimize light exposure and freeze-thaw cycles to preserve the PTD structure.
How does PTD-DBM activate Wnt signalling?
PTD-DBM contains a Dishevelled-binding motif (DBM) that competitively disrupts the inhibitory CXXC5–Dvl interaction. This relieves suppression of the Wnt/β-catenin cascade, promoting target gene transcription. The PTD domain enables intracellular delivery without transfection.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 Shipping: China warehouse — 7–14 day global delivery

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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