What is Kisspeptin-10?
Kisspeptin-10 is a synthetic decapeptide fragment derived from the endogenous peptide hormone kisspeptin, which plays a central role in regulating the hypothalamic-pituitary-gonadal (HPG) axis. It acts by stimulating kisspeptin receptors (GPR54), leading to increased release of gonadotropin-releasing hormone (GnRH).
Through GnRH signaling, kisspeptin-10 influences downstream secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are involved in reproductive hormone regulation. Kisspeptin signaling has been studied for its role in puberty initiation, fertility regulation, and endocrine feedback mechanisms.
Due to its short peptide structure, Kisspeptin-10 is commonly used in endocrine and reproductive hormone research.
Research Applications
- Hypothalamic-pituitary-gonadal axis studies
- GnRH signaling research
- LH and FSH secretion investigations
- Testosterone regulation research
- Fertility and reproductive endocrinology studies
- Puberty signaling pathway investigations
- Hormonal feedback mechanism research
Quick Product Specs
- Form: Lyophilized Powder
- CAS Number: Not standardized (peptide fragment variant)
- Molecular Formula: C₆₃H₈₃N₁₇O₁₄
- Storage: -20°C (long-term) / 2–8°C after reconstitution
- Shelf Life: 24 months unopened
- Type: Hypothalamic Signaling Peptide / GnRH Modulator

