QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse
What is Exemestane?
Exemestane (Aromasin — irreversible steroidal aromatase inhibitor (Type I AI)) is a Small molecule C₂₀H₂₄O₂, MW 296.4. Irreversible steroidal aromatase inhibitor (Type I, mechanism-based) that covalently inactivates CYP19A1 after single binding — unlike reversible non-steroidal AIs. Complete suppression of oestrogen synthesis in all tissues. FDA approved for breast cancer. No rebound aromatisation after discontinuation.
Research Applications
Irreversible CYP19A1 Inactivation
Mechanism-based aromatase inhibition — no enzyme recovery after binding
Type I vs Type II AI
Irreversible (exemestane) vs reversible (anastrozole/letrozole) comparison
Oestrogen Deprivation Research
Complete oestrogen suppression — breast cancer models, bone research
Aromatase Biology
CYP19A1 enzyme kinetics, active site interaction, inactivation mechanism
Breast Cancer Research
FDA-approved compound reference — hormonal breast cancer models
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 107868-30-4 |
| Molecular Formula | C₂₀H₂₄O₂, MW 296.4. |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Steroidal Aromatase Inhibitor |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | As indicated by manufacturer |
