Eloralintide 1mg | MEDI0382 | Dual GLP-1R/GCGR Agonist | Research Grade

Eloralintide (MEDI0382 / Cotadutide) — Dual GLP-1R/GCGR co-agonist — ≥99% HPLC purity, MS confirmed, Janoshik COA. Phase 2: ~10–11% weight loss, ~40–50% liver fat reduction. Research use only.

✓ 99%+ Purity ✓ COA Available
✓ Free Shipping on All Orders ✓ Ships from China (🇨🇳)

$300

Out of stock - join the waitlist. Enter your email and we'll notify you the moment it's restocked.

SKU: QSC-ELORALINTIDE-1MG-1VIAL
Categories: , ,
Brand:

QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse

What is Eloralintide?

Eloralintide (MEDI0382 / cotadutide) is a 31-amino acid dual GLP-1R/GCGR co-agonist developed by AstraZeneca/MedImmune. It simultaneously activates the GLP-1 receptor (appetite suppression, insulin secretion, gastric emptying) and the glucagon receptor (GCGR — hepatic CPT1A upregulation driving direct fatty acid β-oxidation, UCP1-mediated thermogenesis, energy expenditure increase). Phase 2b: ~10–11% weight reduction at 26 weeks. Phase 2 NASH: ~40–50% liver fat reduction (MRI-PDFF) — direct GCGR mechanism independent of body weight loss. The leading dual GLP-1R/GCGR research tool for NASH/MAFLD and hepatic lipid metabolism biology.

Research Applications

Dual GLP-1R/GCGR Pharmacology

GCGR/CPT1A hepatic fat oxidation mechanism; GLP-1R+GCGR co-agonism vs GLP-1R-only reference compounds

NASH / MAFLD Research

Phase 2: ~40–50% liver fat ↓ (MRI-PDFF), ALT normalisation, NASH histology improvement — direct hepatic mechanism

Weight Loss Biology

Phase 2b: ~10–11% weight reduction at 26 weeks; UCP1/BAT thermogenesis via GCGR

Hepatic Lipid Metabolism

CPT1A upregulation, mitochondrial β-oxidation, hepatic glucose production reduction, VLDL/TG biology

vs Semaglutide / Survodutide

Comparative GLP-1R+GCGR vs GLP-1R-only pharmacology; isolated GCGR hepatic mechanism vs tirzepatide/retatrutide

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 1884736-23-5
Also Known As MEDI0382, Cotadutide
Peptide Type Dual GLP-1R/GCGR Co-Agonist (31 AA)
Molecular Weight ~3,968 Da
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Developer AstraZeneca / MedImmune
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (use within 28 days)
Shelf Life 24 months unopened

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇺🇸 USA  ·  🇪🇺 EU  ·  🇬🇧 UK  ·  🇨🇦 Canada  ·  🇦🇺 Australia

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

📋

Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
🧪

General Safety & Handling

🚫

Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

🥽

PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

🌡️

Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

🗑️

Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

🧾

Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

❄️

Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

Peptides
Blends
Search
Track Order
Contact