Dulaglutide 5mg | 20-Vial Kit | GLP-1R Agonist Fc-Fusion | Metabolic Research

Dulaglutide 5mg | 20-Vial Kit — Long-acting GLP-1 receptor agonist (LY2189265) — GLP-1 analogue fused to IgG4 Fc fragment for extended 7–14 day half-life, enabling once-weekly administration in research models. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
✓ Free Shipping on All Orders ✓ Ships from China (🇨🇳)

$650

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SKU: QSC-DULAGLUTIDE-5MG-20VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPSChina Warehouse

What is Dulaglutide??

Dulaglutide (LY2189265, CAS 923950-08-7) is a long-acting GLP-1 receptor agonist consisting of two modified GLP-1 analogue peptides covalently linked via a small peptide linker to an Fc region of human IgG4 — creating a homodimeric fusion protein of ~63 kDa. The GLP-1 moiety is 90% homologous to native GLP-1(7-37) with two amino acid substitutions (Ala⁸→Aib, Gly²²→Glu) that confer DPP-IV resistance. The IgG4 Fc extends half-life to approximately 5 days, enabling weekly dosing in clinical use (Trulicity®). Dulaglutide activates GLP-1R (Gs/cAMP/PKA) — stimulating glucose-dependent insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite via central GLP-1R.

Research Applications

GLP-1R Signalling

Gs/cAMP/PKA/Epac2 pathway, GLP-1R-dependent β-cell cAMP dynamics, receptor internalisation kinetics

β-Cell Biology

Glucose-stimulated insulin secretion (GSIS), β-cell proliferation/survival, PDX-1 expression

Glucagon Suppression

α-cell GLP-1R-mediated glucagon inhibition, hepatic glucose output reduction, hypoglycaemia risk

Obesity & CNS Appetite

Hypothalamic GLP-1R feeding suppression, gastric emptying delay, adipose lipolysis changes

Cardioprotection

GLP-1R cardioprotective signalling, atherosclerosis models, CV outcome comparison vs. other GLP-1RAs

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 923950-08-7
Also Known As LY2189265, Trulicity® active peptide
Molecular Weight ~63 kDa (IgG4-Fc homodimer)
Half-Life ~5 days (IgG4-Fc mediated)
Peptide Type Long-acting GLP-1R agonist Fc-fusion protein
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 Shipping: China warehouse — 7–14 day global delivery

Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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