Dihexa 10mg | 10-Vial Kit | HGF/MET Nootropic Peptide | High-Dose Cognitive Research

Dihexa 10mg | 10-Vial Kit — HGF/MET agonist heptapeptide (PNB-0408) — activates hepatocyte growth factor receptor to drive hippocampal synaptogenesis and dendritic spine density; studied for cognitive enhancement and memory improvement. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$280

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SKU: QSC-DIHEXA-10MG-10VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS8-Region Domestic Shipping

What is Dihexa (High-Dose)??

Dihexa (PNB-0408, CAS 1239264-98-2) is a highly CNS-penetrant HGF/MET-potentiating peptidomimetic that drives de novo synaptogenesis — estimated at 10⁷-fold greater potency than BDNF for new dendritic spine formation. This 10mg/vial high-dose format supports dose-escalation protocols, multi-cohort neurodegeneration studies, transdermal delivery experiments, and long-duration cognitive paradigms where larger quantities per session are required. Molecular formula C₂₄H₃₉N₃O₄, MW 437.58 g/mol.

Research Applications

High-Dose Synaptogenesis

Dose-escalation dendritic spine density, concentration-response at HGF/MET receptor

Extended Cognitive Studies

Multi-week spatial learning, fear conditioning, and NOR paradigms requiring higher peptide reserves

Transdermal Delivery Research

Lipophilicity-driven skin penetration studies, bioavailability comparison vs. sc/ip routes

Neurodegeneration Reversal

High-dose Alzheimer’s-model synapse recovery, AChE-lesion and Aβ model synaptogenesis restoration

Neuroplasticity Mechanisms

LTP, AMPA/NMDA receptor trafficking, PSD-95 clustering under sustained HGF/MET activation

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 1239264-98-2
Also Known As PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Molecular Formula C₂₄H₃₉N₃O₄
Molecular Weight 437.58 g/mol
Mechanism HGF/MET receptor complex potentiation → synaptogenesis — 10mg/vial high-dose
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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