QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Aromasin?
Exemestane (Aromasin) is a steroidal Type I aromatase inhibitor — irreversible “suicide” inhibitor of CYP19A1. Binds the aromatase active site permanently until new enzyme is synthesised. Mechanistically distinct from reversible Type II AIs (letrozole, anastrozole). Research: permanent enzyme inactivation kinetics, hormone-sensitive cancer. CAS 107868-30-4.
Research Applications
Irreversible CYP19A1 Inhibition
Suicide aromatase inhibitor — permanent enzyme depletion kinetics
Type I vs Type II AI
Steroidal irreversible vs non-steroidal reversible — mechanism comparison
Estrogen Suppression
Complete oestradiol suppression — hormone-sensitive cancer models
Enzyme Kinetics
Irreversible inhibitor kinetics — Km/Vmax with substrate turnover
Male Aromatase Research
T:E2 ratio manipulation — aromatase excess syndrome
Quick Specs
| Form | Tablet — 25mg per tablet, 100-tablet bottle |
| CAS Number | 107868-30-4 |
| Molecular Formula | C₂₀H₂₄O₂ |
| Molecular Weight | 296.4 g/mol |
| Compound Type | SERM / Aromatase Inhibitor |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months unopened |

