QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAPharmaceutical-Grade5-Region Domestic Shipping
What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide — injectable coenzyme research compound) is the oxidised form of NAD, the essential coenzyme involved in over 500 enzymatic reactions in human metabolism — MW 663.4. Injectable NAD+ bypasses oral breakdown and provides direct systemic availability. NAD+ is the primary substrate for sirtuins (SIRT1–7), PARPs (DNA repair), and CD38 — central to mitochondrial energy metabolism, DNA repair, circadian rhythm regulation, and cellular stress response. Intracellular NAD+ declines with age.
Research Applications
Sirtuin Activation Research
NAD+-dependent SIRT1–7 deacylase activity — longevity pathway and metabolic gene regulation
DNA Repair (PARP Research)
PARP1/2 ADP-ribosylation and DNA single-strand break repair — NAD+ as limiting substrate
Mitochondrial Biogenesis
SIRT1/PGC-1α axis and SIRT3 mitochondrial protein deacetylation — mitochondrial function research
Cellular Senescence & Aging
Age-related NAD+ decline and restoration — senolytics and longevity research models
Circadian Rhythm Regulation
NAMPT-NAD+-SIRT1 feedback loop in circadian clock gene expression
Quick Specs
| Form | Injectable solution |
| Concentration | 100mg/mL NAD+ |
| Molecular Formula | C₂₁H₂₇N₇O₁₄P₂ |
| MW | 663.4 Da |
| Purity | ≥99% by HPLC — every batch |
| Identity | MS confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Vehicle | Sterile aqueous solution |
| Storage | 2–8°C | Protect from light | Do not freeze |
| Shelf Life | 24 months (unopened) |
