QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COA5-Region Domestic ShippingProapoptotic Peptide
What is Adipotide 2mg?
Adipotide (FTPP — Prohibitin-targeting peptide) is a chimeric proapoptotic peptide that selectively targets the vasculature feeding white adipose tissue. The peptide binds prohibitin on adipose endothelial cells, disrupting mitochondrial function and inducing apoptosis specifically in adipose-feeding blood vessels, causing adipose regression without affecting other tissues. First characterised in NHP (non-human primate) models where it produced substantial fat mass reduction.
Research Applications
White Adipose Vascular Targeting
Selective apoptosis induction in adipose vasculature via prohibitin binding. Research models: DIO rodents, NHP obesity models. Readouts: fat mass (EchoMRI), adipose vascular density, prohibitin expression.
Obesity Pharmacology — Non-GLP-1 Mechanism
Adipotide provides a mechanistically distinct alternative to GLP-1 agonism for obesity research — direct vascular targeting rather than appetite suppression. Enables comparison studies.
Prohibitin Biology Research
Prohibitin (PHB) is expressed on adipose endothelial cells but not other vascular beds. Adipotide exploits this specificity — relevant to PHB receptor biology and targeted delivery research.
Quick Specs
| Product | Adipotide (FTPP) 2mg × 10 Vials (20mg total) |
| Format | Lyophilised powder, 10-vial kit |
| Purity | ≥99% HPLC, MS confirmed |
| Storage | −20°C lyophilised; 4°C reconstituted, 7 days |
| Sequence | CKGGRAKDC-GG-D(KLAKLAK)₂ |
