⚠️ Research Use Only. All compounds sold exclusively for in vitro laboratory research. Not for human or veterinary use. Researchers are responsible for compliance with local regulations.
The Midas Longevity Protocol is the most scientifically comprehensive longevity research stack ever assembled — 12 compounds addressing every major hallmark of biological aging through 10 distinct, non-overlapping biological pathways. Where other stacks address 2–3 aging mechanisms, Midas covers the full spectrum: from mitochondrial cristae repair (SS-31) and senescent cell clearance (FOXO4-DRI) to telomerase activation (Epithalon), thymic immune rejuvenation (Thymosin Alpha-1), and mitochondria-nuclear cytoprotection (Humanin).
12Compounds
120Vials
10Longevity Pathways
≥99%HPLC Purity
8Domestic Regions
10 Longevity Pathways
Sirtuin / Bioenergetics — NAD+ 500mg Mitochondrial electron carrier, sirtuin substrate (SIRT1–7), PARP DNA repair, CD38. NAD+ declines ~50% between ages 40–60 — the foundational longevity intervention.
Critical electron carrier and substrate for SIRT1–7 (metabolic gene regulation), PARPs (DNA repair), CD38 (calcium signalling). NAD+ declines ~50% between ages 40–60. 500mg/vial — highest research concentration available from QSC.
Ala-Glu-Asp-Gly pineal bioregulator. Primary mechanism: telomerase activation to maintain chromosomal telomere length. Also researched for melatonin normalisation and antioxidant enzyme upregulation. Paired with NAD+ for dual-mechanism cellular anti-aging.
TLR9 agonist and thymic peptide (Thymalfasin). Enhances T-cell maturation and proliferation, NK cell cytotoxicity, dendritic cell antigen presentation, and macrophage function. Addresses thymic involution — the age-related collapse of thymic output that drives immunosenescence. Approved as Zadaxin in multiple markets.
Most receptor-selective GH secretagogue available. Stimulates GH without raising cortisol, prolactin, or aldosterone. Combined with CJC-1295 No DAC for synergistic pulsatile GH — improved sleep architecture, skin elasticity, body composition, recovery.
21-AA peptide encoded in the 16S rRNA region of mitochondrial DNA. Activates JAK2/STAT3 and PI3K/Akt for cytoprotection. Inhibits Bax-mediated apoptosis. Researched for neuroprotection, cardioprotection, and beta-cell survival. Unique MDP compound — not present in any other QSC protocol stack.
How Midas Addresses the Hallmarks of Aging
The 12 Hallmarks of Aging (López-Otín et al., 2023, Cell) provide the scientific framework for the Midas Protocol’s compound selection:
Hallmark
Midas Compound(s)
Genomic Instability
NAD+ (PARP activation, DNA repair)
Telomere Attrition
Epithalon (telomerase activation)
Epigenetic Alterations
NAD+ (SIRT1–7 sirtuin regulation)
Loss of Proteostasis
Humanin (Bax inhibition, chaperone support)
Disabled Macroautophagy
NAD+ (SIRT1-mediated autophagy), BPC-157
Mitochondrial Dysfunction
SS-31 (cristae repair), NAD+ (Complex I)
Cellular Senescence
FOXO4-DRI (senolysis), NAD+ (senescence delay)
Stem Cell Exhaustion
GHK-Cu (ECM niche), BPC-157, TB-500
Altered Intercellular Comm.
Thymosin Alpha-1, Humanin, FOXO4-DRI (SASP↓)
Chronic Inflammation
FOXO4-DRI (inflammaging), L-Glutathione, TB-500
Stack Specifications
Total
12 compounds · 120 vials (10 vials per compound)
Form
All 12 lyophilized powder
Purity
≥99% HPLC · MS confirmed · every batch
COA
Janoshik independent — publicly verifiable
Shipping
USA · EU · UK · Canada · Australia · Singapore · Thailand · Vietnam
The Midas Longevity Protocol is a 12-compound, 120-vial research stack targeting 10 hallmarks of biological aging simultaneously. The 12 compounds are: NAD+ 500mg, Epithalon 10mg, GHK-Cu 100mg, SS-31 10mg, FOXO4-DRI 5mg, Thymosin Alpha-1 5mg, BPC-157 10mg, TB-500 10mg, CJC-1295 No DAC 5mg, Ipamorelin 5mg, L-Glutathione 600mg, and Humanin 10mg. Supplied by QSC with ≥99% HPLC purity and Janoshik COA.
What makes the Midas Protocol different from other longevity stacks?
The Midas Protocol is the only research stack to simultaneously address all 10 major longevity research pathways: bioenergetics (NAD+), telomere maintenance (Epithalon), ECM renewal (GHK-Cu), mitochondrial repair (SS-31), senolysis (FOXO4-DRI), immune rejuvenation (Thymosin Alpha-1), tissue repair (BPC-157+TB-500), GH optimization (CJC-1295+Ipamorelin), antioxidant defense (Glutathione), and cytoprotection (Humanin). No other commercially available research stack covers all 10.
What is SS-31 and why is it in the Midas Protocol?
SS-31 (Elamipretide/Bendavia) is a mitochondria-targeted cardiolipin-binding peptide. It stabilizes mitochondrial cristae structure, restores electron transport chain efficiency, and reduces mitochondrial ROS. Mitochondrial dysfunction is one of the 12 hallmarks of aging identified by Lopez-Otin et al. SS-31 is the most targeted mitochondrial repair compound available for research, with Phase 2 clinical data in heart failure and age-related conditions.
What is FOXO4-DRI and why is senolysis important?
FOXO4-DRI is a D-amino acid retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells, triggering their selective apoptosis. Senescent cells accumulate with age and drive chronic inflammation (inflammaging) through the senescence-associated secretory phenotype (SASP). FOXO4-DRI was used in the landmark 2017 Baar et al. Cell study demonstrating selective senescent cell clearance with improvements in fitness, hair density, and kidney function in aged mice.
What is Humanin and why is it unique?
Humanin is a mitochondria-encoded peptide — one of the mitochondrial-derived peptides (MDPs) — discovered in 2001 as a neuroprotectant. It activates JAK2/STAT3 and PI3K/Akt signaling for cytoprotection, inhibits Bax-mediated apoptosis, reduces amyloid beta-induced neurodegeneration, and protects pancreatic beta cells. Unlike other compounds in the Midas Protocol, Humanin targets mitochondrial-nuclear communication and circulating cytoprotection simultaneously.
How does the Midas Protocol compare to the Clavicular Ascension and Venus Protocol?
The Midas Protocol is focused entirely on longevity and anti-aging research — it contains no androgens, no anabolics, and no melanocortin compounds. It adds SS-31 (mitochondrial repair), FOXO4-DRI (senolysis), Thymosin Alpha-1 (immune rejuvenation), and Humanin (cytoprotection) — four compounds absent from both the Ascension Stack and Venus Protocol. Shared compounds with both stacks include NAD+, Epithalon, GHK-Cu, BPC-157, TB-500, CJC-1295, Ipamorelin, and L-Glutathione.
