QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is Tamoxifen (Nolvadex)?
Tamoxifen is a non-steroidal SERM — acts as an ER antagonist in breast tissue (blocking estradiol-driven proliferation) and as a partial ER agonist in bone and uterine tissue. Active metabolite 4-hydroxytamoxifen has ~100× higher ER affinity. Research tool for ER pharmacology, breast cancer models, and HPG axis reactivation research. Research use only.
Research Applications
ER Antagonism Research
Competitive ER blockade, breast epithelial ER-mediated gene suppression
SERM Tissue Selectivity
Antagonist in breast vs agonist in bone/uterus — tissue-selective ER pharmacology
HPG Axis Reactivation
Hypothalamic ER blockade — LH/FSH upregulation, testosterone restoration models
Breast Cancer Research
ER+ cancer cell proliferation inhibition, resistance mechanism studies
4-OH-Tamoxifen Metabolism
CYP2D6-mediated active metabolite formation, pharmacogenomics
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 10540-29-1 |
| Molecular Formula | C₂₆H₂₉NO, MW 371.5 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | Selective Estrogen Receptor Modulator (SERM) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
