QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a selective, cell-permeable NNMT (nicotinamide N-methyltransferase) inhibitor. NNMT inhibition increases SAM (S-adenosylmethionine) availability for cellular methylation reactions, activates NAD⁺ biosynthesis, and promotes adipose tissue browning. Research tool for NNMT biology, methylation capacity, and longevity research. Research use only.
Research Applications
NNMT Inhibition
Nicotinamide N-methyltransferase selective inhibition — enzyme kinetics, selectivity
SAM & Methylation Research
S-adenosylmethionine availability, epigenetic methylation capacity, one-carbon metabolism
Adipose Browning
White-to-brown adipose transition, UCP1 expression, thermogenic activation
NAD⁺ & Longevity
NAD⁺ biosynthesis upregulation, sirtuin activation, cellular energy metabolism
Metabolic Disease Models
Obesity, insulin resistance — NNMT elevation in disease, inhibitor rescue
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 1092351-67-1 |
| Molecular Formula | C₆H₇N₃O, MW 137.1 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | NNMT Inhibitor / Methylation Enhancer |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |
