QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is AICAR?
AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) is an AMP mimetic that activates AMPK — the master energy sensor. Phosphorylated intracellularly to ZMP, mimicking elevated AMP:ATP ratio. Activates fatty acid oxidation, glucose uptake, mitochondrial biogenesis, and autophagy. Classic research tool for energy sensing and exercise mimetic pharmacology. Research use only.
Research Applications
AMPK Activation
pAMPK, pACC, downstream energy sensing cascade — dose-response
Exercise Mimetic Research
Endurance gene programs — running capacity, fibre type shift, PGC-1α
Glucose Metabolism
GLUT4 translocation, insulin-independent glucose uptake, hepatic glycolysis
Fatty Acid Oxidation
CPT1 derepression, β-oxidation flux, ketogenesis interaction
Autophagy & mTOR
mTORC1 suppression, ULK1 activation, autophagy flux quantification
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 2627-69-2 |
| Molecular Formula | C₉H₁₄N₄O₈P, MW 338.2 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | AMPK Activator / AMP Mimetic |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |

