QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is Exemestane (Aromasin)?
Exemestane (Aromasin) is a steroidal suicide aromatase inhibitor — irreversibly inactivates aromatase (CYP19A1) via covalent binding. Structurally similar to androstenedione. Research tool for aromatase enzymology, irreversible enzyme inactivation kinetics, estrogen suppression, and steroidal vs non-steroidal AI comparison. Research use only.
Research Applications
Irreversible Aromatase Inactivation
Suicide substrate kinetics, kcat/kinact determination, CYP19A1 covalent inhibition
Steroidal vs Non-Steroidal AI
Exemestane vs anastrozole/letrozole — mechanism, selectivity, recovery studies
Estrogen Suppression
Estradiol reduction kinetics, tissue estrogen levels, receptor occupancy
Bone Health Research
Estrogen-dependent bone turnover — aromatase inhibition effects on BMD
Post-Aromatase Recovery
New aromatase synthesis after irreversible inactivation — enzyme recovery timeline
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 107868-30-4 |
| Molecular Formula | C₂₀H₂₄O₂, MW 296.4 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | Steroidal Aromatase Inhibitor (Irreversible / Suicide AI) |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |

