QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SynthesisChina Warehouse
What is Isotretinoin (13-cis-Retinoic Acid)?
Isotretinoin (13-cis-retinoic acid) is a synthetic retinoid binding RAR and RXR nuclear receptors. Induces sebocyte apoptosis, reduces sebaceous gland size, normalises keratinocyte differentiation, and has anti-proliferative effects in neuroblastoma. Research tool for retinoid receptor pharmacology, sebaceous biology, and differentiation research. Research use only.
Research Applications
RAR/RXR Pharmacology
Retinoid receptor binding, RARE-mediated transcription, retinoid signalling cascade
Sebaceous Gland Research
Sebocyte apoptosis, sebum suppression, SCD1/FASN pathway modulation
Keratinocyte Differentiation
Follicular hyperkeratinisation inhibition, skin barrier, cornification
Neuroblastoma Differentiation
MYCN suppression, neural differentiation, neurite outgrowth induction
Retinoid Bulk Research
Large-scale receptor binding studies, RARE reporter assays, SAR with isomers
Quick Specs
| Form | Raw bulk powder (crystalline/amorphous) |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 4759-48-2 |
| Molecular Formula | C₂₀H₂₈O₂, MW 300.4 |
| Identity | MS molecular weight confirmed — every batch |
| Compound Type | Retinoid / Retinoic Acid Isomer |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house synthesis — Qingdao, China |
| Storage | Room temperature sealed | cool, dry storage |
| Shelf Life | 24 months (unopened) |

