MGF 2mg | 10-Vial Kit | Mechano Growth Factor | Muscle Satellite Cell Research

MGF 2mg | 10-Vial Kit — IGF-1 Ec splice variant (mechano growth factor) — local tissue isoform of IGF-1 activated by mechanical loading, studied for satellite cell activation and muscle repair independent of systemic IGF-1. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

✓ 99%+ Purity ✓ COA Available
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$200

or
SKU: QSC-FM2-MGF-2MG-10VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS8-Region Domestic Shipping

What is MGF??

MGF (Mechano Growth Factor) is a splice variant of IGF-1 (the Ec isoform in humans, CAS 87081-35-4) produced locally in muscle tissue in response to mechanical loading or damage. The unique E-domain peptide (24 aa) of MGF activates satellite cell proliferation independently of the IGF-1 receptor — acting through a distinct receptor population to expand the myoblast pool before differentiation. After local depletion (~minutes), circulating systemic IGF-1 drives differentiation and protein synthesis. PEGylated MGF extends this half-life significantly for sustained research models.

Research Applications

Satellite Cell Activation

Muscle stem cell proliferation, E-domain receptor signalling, post-injury myoblast pool expansion

Mechano-Transduction

Mechanical loading → MGF splice induction, IGF-1Ec vs. IGF-1Ea isoform comparison

Muscle Repair Models

Eccentric contraction injury, muscle wasting (cachexia, sarcopenia), re-innervation models

IGF-1 Axis Dissection

MGF vs. systemic IGF-1 temporal sequencing, E-domain vs. IGF-1R activation

Neuroprotection

MGF E-domain peptide neuroprotective effects in motor neuron and cortical neuron models

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 87081-35-4
Also Known As IGF-1 Ec splice variant, Mechano-IGF-1
Peptide Type Synthetic IGF-1 splice variant / muscle satellite cell activator
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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