Pinealon (EDR — Glu-Asp-Arg) is a synthetic tripeptide bioregulator designed to target pineal gland biology. It was developed by Prof. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology — the same research group responsible for Epitalon, Thymalin, and other short peptide bioregulators with epigenetic mechanisms.
Unlike most research peptides that bind membrane receptors, pinealon acts intracellularly — penetrating cell nuclei and binding specific DNA sequences to modulate gene expression. This chromatin-binding mechanism allows pinealon to influence transcription of genes involved in circadian rhythm regulation, neuroprotection, and anti-oxidant defence. Research applications include pineal biology, neuroprotection models, and longevity research alongside Epitalon.
Prof. Vladimir Khavinson / St. Petersburg Institute of Gerontology
Related Peptides
Epitalon, Thymalin, Vilon, Cortagen
QSC Purity
≥99% HPLC · MS confirmed · Janoshik COA
Shipping
US Domestic: 2–4 days · International: 5–14 days
Frequently Asked Questions
What is pinealon?
Pinealon (EDR) is a synthetic tripeptide (Glu-Asp-Arg) — a short 3-amino acid peptide designed as a pineal gland bioregulator. It was developed by the St. Petersburg Institute of Gerontology (Prof. Vladimir Khavinson) as part of a peptide bioregulator series targeting tissue-specific epigenetic modulation. Research shows pinealon binds DNA and modulates transcription, with effects on neuroprotection, pineal function, and circadian biology.
How does pinealon work?
Pinealon works via epigenetic/chromatin mechanisms: as a short tripeptide, it penetrates cell nuclei and binds chromatin (specific DNA sequences), modulating the expression of genes involved in circadian rhythms, neuroprotection, and anti-oxidant defence. Unlike receptor-binding peptides, pinealon acts intracellularly on gene regulation. This mechanism is shared with other Khavinson bioregulators (Epitalon, Vilon, Thymalin).
Where can I buy research-grade pinealon?
QSC (qsc-usa.com) stocks research-grade pinealon at ≥99% HPLC purity with Janoshik COA. Ships from US Domestic Warehouse in 2–4 business days. Sold for in vitro laboratory research only.
What is the difference between pinealon and epitalon?
Both are Khavinson peptide bioregulators: Epitalon (Ala-Glu-Asp-Gly, 4 AA) targets telomerase activation and the pineal gland primarily. Pinealon (Glu-Asp-Arg, 3 AA) has a more focused epigenetic mechanism targeting pineal-specific and neuroprotective gene expression. They are complementary in longevity/circadian research protocols.
Buy Research-Grade Pinealon
≥99% HPLC · Janoshik COA · US Domestic 2–4 Days · Research Use Only
Research Use Only: Pinealon is sold by QSC strictly for in vitro laboratory research. Not for human or veterinary use. Not FDA approved for clinical application.
