QSC RESEARCH GRADE
≥99% HPLC PurityMS ConfirmedJanoshik COAIn-House SPPS5-Region Domestic Shipping
What is Cagrilintide?
Cagrilintide (Long-acting amylin receptor agonist (CALCR/RAMP)) is a Amylin analog (fatty acid-conjugated for weekly dosing). Long-acting amylin analog activating the amylin receptor complex (calcitonin receptor CALCR + receptor activity-modifying proteins RAMP1/2/3) via brainstem area postrema and hypothalamic circuits — appetite suppression pathway distinct from GLP-1R. Weekly dosing; combined with semaglutide in CagriSema Phase 3.
Research Applications
CALCR/RAMP Pharmacology
Amylin receptor complex activation — area postrema and hypothalamus
Brainstem Appetite Circuit
Independent of GLP-1R — distinct neuronal appetite suppression
Long-Acting Amylin PK
Weekly fatty acid-conjugated amylin analog pharmacokinetics
CagriSema Reference
Phase 3 component — isolated activity vs combination
vs Pramlintide
Short-acting (pramlintide) vs long-acting (cagrilintide) amylin research
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | Not publicly standardized (peptide analog) |
| Molecular Formula | Sequence-specific long-acting amylin analog |
| Peptide Type | Long-Acting Amylin Receptor Agonist |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |




