5-Amino-1MQ 5mg | 10-Vial Kit | 50mg Total | NNMT Inhibitor

5-Amino-1MQ 5mg — NNMT inhibitor, NAD+ elevation, fat oxidation research. ≥99% HPLC, Janoshik COA. 10-vial kit, 50mg total.

✓ 99%+ Purity ✓ COA Available
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$190

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SKU: QSC-5AMINO1MQ-5MG-10VIAL
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QSC RESEARCH GRADE

≥99% HPLC PurityMS ConfirmedJanoshik COA8-Region Domestic Shipping

What is 5-Amino-1MQ 5mg?

5-Amino-1MQ (5-amino-1-methylquinolinium) is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT). By blocking NNMT, it prevents the methylation and disposal of nicotinamide, raising intracellular NAD+ levels and activating SIRT1-mediated fat oxidation. Research applications include obesity, metabolic syndrome, and adipocyte biology.

Research Applications

Fat Oxidation & Adipocyte Research

NNMT inhibition reduces adipogenesis and promotes lipolysis in white adipose tissue. 3T3-L1 cell model standard for evaluating anti-obesity activity.

NAD+ / SIRT1 Pathway Research

Raising intracellular NAD+ activates sirtuins (SIRT1, SIRT3) — links to longevity, mitochondrial biogenesis, and glucose metabolism pathways.

Metabolic Syndrome Models

DIO mouse models: 5-Amino-1MQ reduces fat mass and improves insulin sensitivity without affecting food intake — distinct from appetite-suppression mechanisms.

Quick Specs

Product 5-Amino-1MQ 5mg × 10 Vials (50mg total)
CAS 1342278-01-6
Format Lyophilised powder, 10-vial kit
Purity ≥99% HPLC, MS confirmed
Storage −20°C lyophilised; 4°C reconstituted, 7 days
Reconstitution Bacteriostatic water or DMSO

Certificate of Analysis (COA)

For the latest Certificate of Analysis (COA), please email us with your request.

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
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🧬 PubMed Research — 5-Amino-1MQ
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Source: PubMed / NCBI  ·  Last 10 years  ·  Refreshed every 24 hours  ·  For research reference only — not clinical guidance.

⚠️ RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION

QSC products are strictly for in vitro and in vivo laboratory research. Not intended for diagnostic, therapeutic, or personal use.

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Research Use Disclaimer

All QSC products are strictly for laboratory, scientific, and research use only. They are not for human consumption, medical treatment, diagnosis, or disease prevention.

By purchasing or using QSC products, you confirm:

  • You are a qualified researcher or acting under the supervision of one.
  • Products will only be used for legitimate research purposes.
  • Products are not evaluated by the FDA or any regulatory authority for human use.
  • You assume all responsibility for legal compliance, proper handling, and storage.
  • You meet the legal age requirement in your jurisdiction.
No Warranty: Products are sold “as is,” with no express or implied warranties regarding efficacy, safety, or suitability. Results in research may vary. QSC is not responsible for outcomes, interpretations, or conclusions drawn from any studies conducted using these products.
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General Safety & Handling

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Not for Human Use

These compounds are for research only. Any off-label, personal, or clinical use is strictly outside the intended scope of supply.

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PPE Required

Always use appropriate personal protective equipment (gloves, lab coat, eye protection) when handling peptides.

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Storage Compliance

Follow product-specific storage conditions to maintain identity, purity, and biological activity.

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Proper Disposal

Dispose of all materials in accordance with institutional biosafety, chemical waste, and hazardous material protocols.

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Verify Quality

Janoshik COAs are available on every product page. Verify batch identity (MS confirmed) and purity (≥99% HPLC) before use.

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Peptide Storage Guidelines

🌑 Light-protected💧 Low moisture🌡️ Stable temperature🔬 Sterile handling

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